A 3-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, for the treatment of dentine hypersensitivity. All rights reserved. Colgate Sensitive Pro-Relief Original Toothpaste This toothpaste gives you the freedom to forget about tooth sensitivity. Correspondence to These ingredients resulted in rapid fluorapatite crystallisation at exposed tubular ends of dentin [12]. FCPS was incorporated in OTC dentifrice with calcium, low contents of fluoride, and high contents of phosphate ions. Treatments provided to the patients were OTC dentifrices marketed with the claim of immediate pain relief in DH. A study evaluating the efficacy of strontium acetate relative to arginine-based dentifrices was conducted by West et al. This study investigated the relief from pain in DH in one minute after applying over the counter (OTC) dentifrices with Pro-Argin and strontium acetate and directly compared them with fluoro-calcium phospho-silicate (FCPS)-based dentifrices for immediate and sustained inhibition of painful stimulus provoking DH. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Colgate-Palmolive Company 2018. This clinical trial was not funded by any agency in public, commercial or not-for-profit sectors. fluorides, arginine, strontium, and bioactive glasses (BAG) [4] and in-office application of bioactive formulations such as glutaraldehyde, resin-based bonding agents and restorative materials, amorphous calcium phosphate based-tooth mousse, and lasers in the dental clinics [5]. reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. 2018;9(3):3306. Colgate-Palmolive Company 2018. SEALS & REPAIRS: Pro-Argin technology helps to seal and repair the sensitive areas of teeth. Work with Colgate Professional to help provide better oral care to your patients. [16] in a systematic review in 2015. Layer T, Hughes N. Evidence for the efficacy of an 8% strontium acetate dentifrice for instant and lasting relief of dentin hypersensitivity. *with direct application and daily brushing. These measures facilitated behaviour modification together with the promotion of knowledge and understanding in the society about DH. Another study by Vu Pham and Anh Nguyen reported clinical improvement in DH by 38.9% on SCASS and 40.2% on VAS for mechanical stimulated DH immediately after application of Pro-argin [25]. Product Details For instant relief, apply directly to the sensitive tooth with finger tip, and massage gently for 1 minute, once a week or less frequently. For lasting relief and gum protection, apply twice daily using a sensitive toothbrush, making sure to brush all surfaces of teeth including sensitive areas. These toothpaste Can be used after the Colgate Sensitive Pro-Relief Desensitizing Paste. Dentin hypersensitivity treatments work in one of two ways. Privacy With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth (with continued use twice a day). This trial was registered in an ICMJE approved registry at https://clinicaltrials.gov/) under protocol Identifier: NCT04249336 [19] following the CONSORT guidelines [20] for parallel-group randomized trials after approval from the Institutional Review Board of Dow University of Health Sciences with reference no. Mode of action studies on a new desensitizing dentifrice containing 8.0% arginine, a high cleaning calcium carbonate system and 1450 ppm fluoride. Help Caregivers Understand Caries | Colgate Professional, compared to a leading brand of desensitizing toothpaste, Colgate Sensitive Pro Relief Repair and Prevent, Colgate Sensitive Pro Relief Enamel Repair, Colgate Sensitive Pro Relief Multi Protection. The first post-treatment measure of SCASS and VAS scores was obtained immediately after removing dentifrices from teeth. Mason S, Hughes N, Sufi F, Bannon L, Maggio B, North M, et al. Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. We provided oral hygiene instructions and ways of relieving their pain from DH to improve their quality of life. [32] reported statistically significant improvement in mechanical stimulated DH with Pro-argin immediately after topical application relative to 8% strontium Acetate in 2016. Hines D: Poster #0742 March 2018 AADR. A meta-analysis by Grnberg et al. Product Details Page . 2015;42(2):13141. Zinc helps strengthen gums and prevent gum recession a key cause of sensitivity1,2,3. 2013;41(2):18794. Published literature [16, 31, 43] has determined that all previous trials on treating DH were conducted on smaller samples, which might have prevented the results from being extrapolated on the general population. Comparative evaluation of desensitizing efficacy of dentifrice containing 5% fluoro calcium phosphosilicate versus 5% calcium sodium phosphosilicate: a randomized controlled clinical trial. DH most commonly involves the facial surfaces of maxillary and mandibular permanent teeth. If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. J Clin Dent. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Further, it leaves a durable, mineral-enriched layer on the exposed dentin to help protect against future dentin hypersensitivity. 2019;40(10):6537 (quiz 8). Innehller slipmedel med ltt polerande effekt p flckar samt fluor som minskar risken fr karies. Apotekets varuid 29483 Varunummer 207000 Kategori Tandkrm, Ilningar i tnderna Varumrke Participants were randomly allocated to four treatment arms and randomly assigned with OTC dentifrices having FCPS, Pro-argin, strontium acetate, and sodium fluoride (NaF) with an allocation ratio of 1:1:1:1. However, we can conclude that both Pro-argin and strontium acetate-based dentifrices disrupt the pathophysiology of DH and are effective for immediate pain relief even one minute after application on sensitive teeth. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. With regular use, the Pro-Argin formula builds a long-lasting protective barrier that acts like a seal against sensitivity. Mahmoodi B, Wood R, Cook R. Protection and acid resistivity of bioactive-glasses, arginine and calcium silicate. J Clin Dent. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Product Details Characteristics and Benefits Characteristics: Unique Pro-Argin TM/MC technology based on natural process of tubule occlusion Participantswere strictly advised to refrain from acidic food and drink intake at least four hours before following up visit. YYYY Colgate-Palmolive Company. The authors declare that they have no competing interests (financial and non-financial) related to the article. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. Indian J Dent Sci. 2020;99(5):51422. Purchased in August 2019 at Coles for $5. It improves gum health and helps reduce factors that contribute to gum recession, a leading cause of tooth sensitivity. Another study by Hines et al. Participants analyzed per group were more than thirty fulfilling the requirement of Holland's guidelines for conducting clinical trials for the management of DH [42]. Colgate Tandpasta Sensitive Instant Relief Whitening. The prevalence of DH was found to vary from about 5 to 62% owing to the use of different diagnostic and measuring tools and age groups in the published literature, with the best average estimate of 34% worldwide [3]. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. TVC Category: Colgate Tooth Paste Benefits Clinically proven sensitivity relief. WAF has contributed to revising the manuscript critically and contributed to statistical analyses. They don't. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. Individuals either with dental caries, heavily restored, or cracked teeth, or with orthodontic or prosthetic appliances, or with localised or generalised gingivitis or pulpitis and heavy calculus or using any desensitising toothpaste or mouth wash or any other desensitising products up to six weeks before the study were excluded from this trial. Listing a study does not mean it has been evaluated by the U.S. Federal Government. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. The comparative evaluation was done for the clinical efficacy of Pro-argin and 8% strontium acetate, and a statistically significant (p>0.05) difference was not found between these two formulations in the current study. Gentle whitening formula. Directions * with direct application and daily brushing Benefits Exclusive Pro-Argin formula Prevents sensitivty coming back 2. Another study by Hines et al. All the treatment groups subjected to testing in the present study revealed a considerable clinically significant symptomatic reduction in DH relative to the pre-treatment condition that was also statistically significant. There was a significant (p<0.001) reduction of 45.7% with Pro-argin, 37.6% with 8% strontium acetate, 18.1% with FCPS, and 15.2% with NaF-based dentifrices relative to baseline on SCASS after one-minute application on sensitive teeth. For patients in the dental chair, it can be used to rapidly ease hypersensitivity pain, facilitate examinations and make dental procedures more comfortable. J Clin Dent 20 (2009), special issue 17-22, 3. Nathoo S et al. PubMedGoogle Scholar. Exclusive Pro-Argin formula. Statistical Package for the Social Sciences software v.21.0. 2017;2017:2. [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). 2009; 20 (Spec Iss): 1722. California Privacy Statement, J Dent. Am J Dent. The permanent management of DH is being investigated with the remineralisation potential of bioactive agents in dentinal tubules. Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. These findings were similar to a previous study conducted by Schiff et al. Prevalence of dentin hypersensitivity: systematic review and meta-analysis. 1997;24(11):80813. The findings agreed with another in vitro trial by Mahmoodi et al. Pessoa OF, Loretto SC, Maia LC. SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste with Pro-Argin Technology and Zinc. The clinical significance of this study can be highlighted by the fact that this was a person-centred clinical trial where patients were the prime focus where thepatients suffering from DH. Ashwini S, Swatika K, Kamala DN. 4.4 5 0 198 198 Colgate Sensitive Pro-Relief Gum Therapy toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. Dent Health Curr Res. Pro-Argin Technology works through a natural process of dentin tubule occlusion that attracts arginine and calcium carbonate to the dentin surface to form a protective seal that provides instant relief.2 This toothpaste prevents sensitivity coming back by building a protective barrier that acts like . Therefore, the first null hypothesis was that mean scores for pain due to DH among different treatment groups for immediate relief remain. Manage cookies/Do not sell my data we use in the preference centre. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Google Scholar. Klubpris: 25,46 kr. Contemp Clin Dent. 2015;28(1):404. These then interact to form a complex with positive charge. 1 Nathoo et al. No side effects, apart from money not well spent. These fluorapatite crystals were less susceptible to acidic dissolution than hydroxyapatite crystals and thus were more desirable [13]. https://doi.org/10.1186/s12903-021-01864-x, DOI: https://doi.org/10.1186/s12903-021-01864-x. J Dent Res. Colgate uses need to categorize. Colgate Total with stannous fluoride also offers more benefits than ever before, including sensitivity relief, improved enamel strength* and odor neutralization* (*based on in vitro studies).Colgate Total Advanced Whitening is a tooth whitening toothpaste that provides stain removal and prevention. ClinicalTrial.gov: National Library of Medicine (US). Colgate Sensitive Instant Relief Repair & Prevent tandkrm ger dig kliniskt bevisad lngvarig lindring mot ilningar i tta veckor nr du anvnder den tv gnger om dagen. Was this answer helpful? There was statistically no significant difference in the baseline characteristics of gender, age, baseline mean scores of clinical parameters of SCASS, and VAS used for mechanical and water jet stimuli between the four treatment groups (p>0.05). In addition, one-Way ANOVA with Post Hoc Tukey for pair-wise comparison was used to compare treatment groups computing percent change from baseline with formula (post-application mean scores-baseline mean scores/baseline mean scores). Springer Nature. A randomised, controlled, triple-blinded clinical trial was conducted with 140 participants clinically diagnosed with DH and equally randomized into four groups with parallel treatment assignment of FCPS, Pro-Argin, 8% strontium acetate, and sodium fluoride-based OTC dentifrices, and tested for DH with air blast, mechanical, and water jet stimuli on SCHIFF cold air sensitivity scale (SCASS) and visual analogue scale (VAS) at interim efficacy intervals of one minute, three days, two, four, and six weeks, subsequently. A meta-analysis by Yang et al. The statistician was also kept blinded. Colgate SENSITIVE INSTANT Relief tannkrem med Pro-Argin teknologi gir umiddelbar* og langvarig smertelindring av ising i tennene. The current study outcomes showed significant decrease in pain scores of air-blasts and water jet stimulated DH with FCPS based dentifrices compared to Pro-argin and 8% strontium acetate after two, four, and six weeks subsequently, as depicted in Tables 4 and 5. J Clin Dent 2009; 20 (Spec Iss): 17-22. 2016;8:114. However, there is a substantial possibility that these fluoridated dentifrices can reduce DH. However, they also suggested further comparative evaluations of two dentifrices with large sample sizes as limited scientific evidence was found in previous studies [16]. 2020;12(2):87. Free postage. Modified bass brushing method was demonstrated on the same model before the first application of dentifrices in the dental clinic. SHOULD A PATIENT CONTINUE USING Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE ONCE THE DENTINE SENSITIVITY HAS GONE? The total sample size was 140 participants, with thirty-five in each group. Grnberg C, Bauer F, Crispin A, Jakob M, Hickel R, Draenert ME. (US). 2010;11:32. Balevi B. Table 4 demonstrates a comparison between treatment groups observing better clinical efficacy in managing DH on SCASS. Colgate SENSITIVE Instant(Pro) Relief Enamel Repair Toothpaste 75ml (Pck 4,6,12) 15.99 to 39.99. Article Dziki unikalnej formule Pro-Argin z arginin, wzmacnia szkliwo zbw i tym samym staj si one bardziej odporne na dziaanie kwasw. When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. Colgate Sensitive Instant* Relief Enamel Repair Toothpaste gives you clinically proven lasting relief** from sensitivity for 8 weeks when you use it twice a day. OTC dentifrices were applied and massaged gently with the applicator on at least two sensitive teeth per subject at two different sites, including cementoenamel junction and exposed dentinal surface, by the doctor in the office during the first visit. Soft tissues were isolated with cotton rolls, and adjacent teeth were isolated with cotton pellets. For more great Dental Care products like toothpaste and mouthwash, continue browsing online and buy in-store at B&M. Colgate Sensitive Instant Relief Toothpaste 75ml Product code: 326795 2.49 Subject to availability - visit your nearest store 3Intervention for Group C denotes Sensodyne Rapid Action. 2012;12(3):2208. Therefore, the current study outcomes were analysed by parametric and non-parametric statistical tests after assessing the normal distribution of data and equality of variances with Shapiro Wilk statistics. in 2019 using BioMin F and Pro-argin. Table 6 presents the change in the mean scores on VAS against waterjet stimulus from baseline to subsequent efficacy interval within each treatment arm. This toothpaste contains a unique formula that blocks the pathways to pain instantly Its clinically proven formula provides INSTANT RELIEF from the first usage, LONG-LASTING RELIEF with twice everyday use. Participants were asked to pick up the envelope from the box. Explore the videos and articles found on this page to assist in better oral care. Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Madurai: Best Dental Science College; 2020. The relief from sensitivity offered by Colgate Sensitive Pro Relief is proven to last. Pro-Argin showed a greater reduction in DH with mean scores of (1.340.68) (4.201.70) (3.052.17) followed by strontium acetate (1.570.81) (4.651.87) (3.751.97) on SCASS and VAS for mechanical and water jet stimuli, one minute after application. Felix J, Ouanounou A. Dentin hypersensitivity: etiology, diagnosis, and management. Thank you for your feedback. Difference in effectiveness between strontium acetate and arginine-based toothpastes to relieve dentin hypersensitivity. Children 6 years and younger: use a pea-sized amount for supervised tooth brushing to minimise swallowing. Pashley D. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. Therefore, in the current study, we used a dental explorer and the air blast and water jet stimuli from the triple syringe of the dental unit for testing DH to control the subjective variations in treatment response. Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). Pro-Argin technology is occlusive. Mintsmak. 2 Docimo et al. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. J Evid Based Dent Pract. J Dent. 2018;2018:110. According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. In addition, the frequency of participants diagnosed with DH using air blast stimulus was observed as 36.8% at the time of enrolment in the six-week clinical trial that was found consistent with findings of a survey report demonstrating 36.4% frequency of DH among adults in Karachi, Pakistan [24]. The maximum sampling time was 15min. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. It is clinically proven for instant and lasting Sensitivity relief* How does it work?
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